Expresión de búsqueda: DNA TOPOISOMERASE IV 
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Descriptor Inglés:   DNA Topoisomerase IV 
Descriptor Español:   ADN topoisomerasa IV 
Descriptor Portugués:   DNA Topoisomerase IV 
Sinónimos Inglés:   Topo IV
Topoisomerase IV
Topoisomerase IV Subunit A
Topoisomerase IV Subunit B
Topoisomerase IV, DNA
parC Gene Product
parC Gene Product, Topo IV
parC Protein
parE Gene Product
parE Gene Product, Topo IV
parE Protein  
Categoría:   D08.811.399.403.741.224
D12.776.097.256
Definición Inglés:   A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication. 
Nota Histórica Inglés:   2002; use DNA TOPOISOMERASE IV (NM) 1991-2001 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   36090 
Identificador Único:   D027101 

Ocurrencia en la BVS:
 

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